The lighting design for the Block Museum incorporates careful integration of natural lighting as well as a flexible system for electric lighting. Natural light is controlled by low-transmission glass on the front wall, as well as light control shades.

Lighting for the Print, Drawing, and Photography Study Center includes full-range intensity control and is carefully filtered to eliminate ultraviolet wavelengths. In the Auditorium, the lighting is designed to provide appropriate environments for lectures, symposia, concerts and film exhibition.